Possible prevention and treatment of steroid-induced osteoporosis.

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چکیده

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Possible prevention and treatment of steroid-induced osteoporosis.

Patients with steroid-induced, juvenile and senile osteoporosis were studied using balance techniques. The changes in calciun and phosphorus balance associated with glucocorticoid therapy were corrected with vitamin D and bendrofluazide given in combination. No hypercalcaemia occurred in osteoporotic patients who continued to receive glucocorticoids. Calcium and phosphorus balance was also impr...

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Prevention and Treatment of Corticosteroid-Induced Osteoporosis

Osteoporosis is one of the most serious complications of corticosteroid treatment. Loss of bone mineral density (BMD) and fractures occur early in the course of corticosteroid treatment, and thus early recognition of fracture risk and effective intervention based on evidence-based-medicine (EBM) are needed. A study of meta-analysis representing the highest level in a hierarchy of evidence showe...

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Steroid-induced osteoporosis.

INTRODUCTION Corticosteroids have major effects on calcium metabolism, leading to accelerated osteoporosis and fracture. METHODS This review will attempt to summarise current knowledge about their effects in light of new information and important remaining questions, especially with respect to management of this common condition. RESULTS Corticosteroids affect bone through multiple pathways...

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Management of Steroid-Induced Osteoporosis

Chronic use of corticosteroid is the most common secondary cause of osteoporosis. Contrary to previous belief apart from the primary or the idiopathic type, it occurs in all racial groups, both genders, and at any age. In a large cross sectional study in which 229 corticosteroid users (mean age 61 years, ≥6 months of prednisone, ≥5 mg/day) were compared with 286 controls not taking corticostero...

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ژورنال

عنوان ژورنال: Postgraduate Medical Journal

سال: 1978

ISSN: 0032-5473

DOI: 10.1136/pgmj.54.630.249